Santa Cruz district is located in the historical part of Seville. There are numerous bus and tram lines that can take you here. You may use the tram line T1. The tram stop where you should exit is called Archivo de Indias. You may also use the following bus lines: 5, A3, A4 or A8. You should exit at the bus stop called: Menéndez Pelayo (Jardines de Murillo).